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Natural and Medical Sciences Institute
at the University of Tuebingen

The NMI conducts cutting-edge applied research and development at the interface of the life sciences and materials sciences.

Our core competencies include pharma and biotechnology, biomedical technology, as well as surface and interface technology.

Top scientists perform specialist services in laboratories accredited according to DIN EN ISO / IEC 17025.



News and Events
NMI achieving results

Annual report 2008/2009
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Lectures and Conferences:

MEA 2010



NMI publications:

Sequential multiplex analyte capturing for phospho-protein profiling
Oliver Poetz, Tanja Henzler, Michael Hartmann, Cornelia Kazmaier, Markus F. Templin, Thomas Herget, and Thomas O. Joos
Mol Cell Proteomics mcp.M110.002709First Published on August 3, 2010, doi:10.1074/mcp.M110.002709


Towards next generation plasma 1 profiling via heat-induced
epitope retrieval and array-based assays
Jochen M. Schwenk, Ulrika Igel, Maja Neiman, Hanno Langen, Charlotte Becker,
Anders Bjartell, Fredrik Ponten, Fredrik Wiklund, Henrik Grönberg, Peter Nilsson,
and Mathias Uhlen
MCP Papers in Press. Published on August 6, 2010

Biocompatible molecularly imprinted polymers for the voltage regulated uptake
and release of L-glutamate in neutral pH solutions
E. von Hauff, K. Fuchs, D. Ch. Hellmann, J. Parisi, R. Weiler, C. Burkhardt, U. Kraushaar and E. Guenther
Biosensors and Bioelectronics, available online: 16-JUL-2010


Suppression of adverse angiogenesis in an albumin-based hydrogel for articular cartilage and intervertebral disc regeneration.
Scholz B, Kinzelmann C, Benz K, Mollenhauer J, Wurst H, Schlosshauer B.
Eur Cell Mater. 2010 Jul 13;20:24-37.

A novel gelatin sponge for accelerated hemostasis.
Hajosch R, Suckfuell M, Oesser S, Ahlers M, Flechsenhar K, Schlosshauer B.
J Biomed Mater Res B Appl Biomater. 2010 Aug;94(2):372-9.

Analysis of non-canonical fibroblast growth factor receptor 1 (FGFR1) interaction reveals regulatory and activating domains of neurofascin
Katja Kirschbaum, Martin Kriebel, Eva Ursula Kranz, Oliver Poetz and Hansjuergen Volkmer
J Biol Chem October16, 2009;284(42):28533-42.

Protein microarrays: effective tools for the study of inflammatory diseases.Yu X, Schneiderhan-Marra N, Hsu HY, Bachmann J, Joos TO.Methods Mol Biol. 2009;577:199-214.

Microsphere-based co-immunoprecipitation in multiplex.Poetz O, Luckert K, Herget T, Joos TO.Anal Biochem. 2009 Aug 7. [Epub ahead of print]

Magnetic bead-based detection of autoimmune responses using protein microarrays.Gantelius J, Hartmann M, Schwenk JM, Roeraade J, Andersson-Svahn H, Joos TO.N Biotechnol. 2009 Aug 5. [Epub ahead of print]


Ordering of Fe3O4 Nanoparticles in Polyelectrolyte Multilayer Films
M. Kolasinska, T. Gutberlet and R. Krastev
Langmuir, 25(17), (2009)10292-10297

Neutron Reflectometry Study of Swelling of Polyelectrolyte Multilayers in Water Vapours: Influence of Charge Density of the Polycation
R. Köhler, I. Dönch, P. Ott, A. Laschewsky, A. Fery, and R. Krastev
Langmuir (2009) ASAP
 
Absorption of Light and Heavy Water Vapours in Polyelectrolyte Multilayer Films
C. Delajon, Th. Gutberlet, H. Möhwald, R.Krastev
Colloids and Surfaces B: Biointerfaces (2009) ASAP


Strategies for inducing the formation of bands of Büngner in peripheral nerve regeneration
Ribeiro-Resende, V. T., Koenig, B., Nichterwitz, S., Oberhoffner, S., Schlosshauer, B.
Biomaterials. 2009 Oct;30(29):5251-9. Epub 2009 Jul 26.


Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes
Gavenis, K., Schumacher, C., Schneider, U., Eisfeld, J., Mollenhauer, J., Schmidt-Rohlfing, B.
Mol Cell Biochem. 2009 Jan;321(1-2):135-43. Epub 2008 Oct 4.


Phase-sensitive X-ray imaging of synovial joints
Li, J., Zhong, Z., Connor, D., Mollenhauer, J., Muehleman, C.
Osteoarthritis Cartilage. 2009 Mar 24.


Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Pirnia, F., Pawlak, M., Thallinger, G. G., Gierke, B., Templin, M. F., Kappeler, A., Betticher, D. C., Gloor, B. and  Borner, M. M.
Proteomics 2009, 9, 3535-3548.

Förster resonance energy transfer-based total internal reflection fluorescence reader for apoptosis.
Bruns, T., Angres, B., Steuer, H., Weber, P., Wagner, M., Schneckenburger, H.
Journal of Biomedical Optics 2009


Nerve fibroblast impact on Schwann cell behavior
Dreesmann, L., Mittnacht, U., Lietz, M., Schlosshauer, B.
European Journal of Cell Biology, Feb. 2009

Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS)
Bigalke, B., Stellos, K., Weig, H.J., Geisler, T., Seizer, P., Kremmer, E., Pötz, O., Joos, T., May, A.E., Lindemann, S., Gawaz, M.
Basic Res Cardiol. 2009 Feb.


Neuroprotective effect of transretinal electrical stimulation on neurons in the inner nuclear layer of the degenerated retina.
Schmid, H., Herrmann, T., Kohler, K., Stett, A.
Brain Res Bull 2009
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